Yes 180 can be mixed with water, but it's not the best option. 180 is not to be shaken with water as it simply will not dissolve (doesn't contain the chemicals that allow this to happen). We always recommend a smoothie.
180 Protein+ Superfood raw ingredients are ground finally and as there are no chemicals or binding agents etc, the blend will not dissolve. Think of it more of a whole food that's high in protein. There are countless recipes and articles on our blog that you should find helpful.